In 1820 the Regent's Canal was opened, linking Paddington to the Thames at Limehouse.
By 1862 railways had reached Euston, Paddington, King's Cross and St Pancras, but were prevented from going further by Euston and Edgware Roads.
In 1863 The Metropolitan Railway (the shallow Underground Line) linked the main Line stations. About 1900 the deep Tube lines were cut.
In 1970 Westway opened up Edgware Road to the national Motorway system. In 1998 the Heathrow Express brought the airport within 15 minutes travelling. Sometime in the future Cross Rail will link Paddington, Euston, King's Cross and Stratford East.